Nicotine ditartrate

Nicotine ditartrate
  • CAS No.:65-31-6
Other grades of this product :
Nicotine ditartrate Basic information
Product Name:Nicotine ditartrate
Synonyms:(-)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-bitartrate salt;(-)-Nicotine/L-Tartaric acid,(1:2);(S)-Nicotine/(2R,3R)-Tartaric acid,(1:2);3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate;(-)-Nicotine dirartate;(S)-(-)-1-Methyl-2-(3-pyridyl)pyrrolidine(+)-ditartratesalt;Nicotine Bitartrate anhydrous;(-)-Nicotine ditatrate
CAS:65-31-6
MF:C18H26N2O12
MW:462.41
EINECS:200-607-2
Product Categories:EXLAX
Mol File:65-31-6.mol
Nicotine ditartrate Chemical Properties
Melting point 90°
alpha D20 +26° (c = 10)
storage temp. Desiccate at RT
solubility H2O: 50 mg/mL
form powder
color white to off-white
optical activity[α]/D +20 to +26°, c = 1.0 in water
InChIKeyRFEJUZJILGIRHQ-UHFFFAOYSA-N
CAS DataBase Reference65-31-6(CAS DataBase Reference)
EPA Substance Registry SystemPyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) (65-31-6)
Safety Information
Hazard Codes T+,N
Risk Statements 26/27/28-51/53
Safety Statements 13-28-45-61
RIDADR UN 1659 6.1/PG 2
WGK Germany 2
RTECS QT0350000
HazardClass 6.1(a)
PackingGroup II
Hazardous Substances Data65-31-6(Hazardous Substances Data)
MSDS Information
Nicotine ditartrate Usage And Synthesis
Usesnicotinyl acetylchloline receptor agonist, ectoparasiticide
Usescathartic, laxative
General DescriptionPotent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions.
Biological ActivityNicotinic acetylcholine receptor (nAChR) agonist (K i values are 1, > 1000, 4000 and 7130 nM at α 4 β 2, α 1 β 1 δ γ , rat α 7 and human α 7 respectively). Exhibits vasoconstrictive, hypertensive and prothrombotic activity in vivo .
Biochem/physiol ActionsProduct does not compete with ATP.
Safety ProfilePoison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and CO. See also NICOTINE.
Nicotine ditartrate Preparation Products And Raw materials

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