STROPHANTHIDIN

STROPHANTHIDIN
  • CAS No.:66-28-4
Other grades of this product :
STROPHANTHIDIN Basic information
Product Name:STROPHANTHIDIN
Synonyms:19-oxo-cardogenen-(20:22)-triol-(3-beta,5,14);3,5,14-trihydroxy-19-oxo-,(3-beta,5-beta)-card-20(22)-enolid;3,5,14-trihydroxy-19-oxocard-20(22)-enolide;3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolid;3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolide;3-beta,5,14-trioxy-19-oxo-carden-(20:22)-olid;3-beta,5,14-trioxy-19-oxo-digen-(20:22)-olid;5-beta-hydroxy-19-oxodigitoxigenin
CAS:66-28-4
MF:C23H32O6
MW:404.5
EINECS:200-626-6
Product Categories:Sterol Lipids;Aldehydes;Biochemicals and Reagents;Building Blocks;C13-C60;Carbonyl Compounds;Chemical Synthesis;Conjugates;Lipids;Organic Building Blocks
Mol File:66-28-4.mol
STROPHANTHIDIN Chemical Properties
Melting point 169°C
alpha D25 +43.1° (c = 2.8 in methanol)
Boiling point 446.1°C (rough estimate)
density 1.432±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 1.4593 (estimate)
storage temp. -20°C
solubility ethanol: complete50mg/mL, clear, colorless to yellow
pka13.92±0.70(Predicted)
Safety Information
Hazard Codes T+
Risk Statements 26/27/28
Safety Statements 22-36/37/39-45
RIDADR UN 2811 6.1/PG 1
WGK Germany 3
RTECS FH5425000
ToxicityLD100 i.v. in cats: 0.337 mg/kg (Graebner, Geisel)
MSDS Information
ProviderLanguage
SigmaAldrich English
STROPHANTHIDIN Usage And Synthesis
Usescardiotonic
UsesStrophanthidin was used to synthesize acetylstrophanthidin and the effect on neurotransmitter release from dog saphenous vein was studied.3
General DescriptionThis substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol ActionsStrophanthidin is a cardiotonic steroid that elevates the activity of Na+/K+-ATPase in cardiac myocytes.1 It decreases the potassium content and raises the sodium content in rabbit renal cortex slices.2
STROPHANTHIDIN Preparation Products And Raw materials
Raw materialsCYMARIN
Preparation Productsα-D-Glucopyranose, 6-O-β-D-glucopyranosyl--->D-glucose

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