DESTRUXIN A

DESTRUXIN A
  • CAS No.:6686-70-0

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
DESTRUXIN A Basic information
Product Name:DESTRUXIN A
Synonyms:3-Ethenylcyclo(D-Lac-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-βAla-);N-[N-[(2R)-1-Oxo-2-hydroxy-4-pentenyl]-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-]-β-alanine lactone;N-[N-[(R)-2-Hydroxy-1-oxo-4-pentenyl]-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-]-β-alanine lactone;Destruxin A from Metarrhizium anisopliae;Destruxin A, 98%, from Metarhizium anisopliae;DESTRUXIN A;destruxin A from metarhizium anisopliae;Cyclo[N-methyl-L-alanyl-β-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl]
CAS:6686-70-0
MF:C29H47N5O7
MW:577.71
EINECS:
Product Categories:Apoptosis and Cell Cycle;Cell Cycle;Cell Cycle Regulators
Mol File:6686-70-0.mol
DESTRUXIN A Chemical Properties
Melting point 188-189 °C
Boiling point 875.6±65.0 °C(Predicted)
density 1.18±0.1 g/cm3(Predicted)
storage temp. -20°C
pka13.53±0.70(Predicted)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38-48
Safety Statements 26-36-45
WGK Germany 3
RTECS HH1500000
HS Code 2933790090
MSDS Information
ProviderLanguage
SigmaAldrich English
DESTRUXIN A Usage And Synthesis
UsesDestruxin A from Metarrhizium anisopliae has been used for immersion and inoculation bioassay in Rhipicephalus (Boophilus) microplus. It has been used as a transport inhibitor in Drosophila melanogaster.
Biochem/physiol ActionsDestruxin A is a cyclic hexadepsipeptide produced by fungus causing paralysis and death in insects. May suppress the insect immune response. Possesses an inhibitory activity on leukemic cell proliferation, decreasing the number of cells in G2/M phase. It is virustatic against arboviruses.
DESTRUXIN A Preparation Products And Raw materials

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