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| TN ANTIGEN Basic information |
| TN ANTIGEN Chemical Properties |
| Melting point | 198-201°C | | Boiling point | 701.2±60.0 °C(Predicted) | | density | 1.51±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Water | | form | Solid | | pka | 2.05±0.10(Predicted) | | color | Off-White to Yellow | | Stability: | HYGROSCOPIC |
| TN ANTIGEN Usage And Synthesis |
| Chemical Properties | TN ANTIGEN is Yellow Solid
| | Uses | A cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines. | | Uses | TN ANTIGEN is a cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines
| | General Description | Tn antigen?is a truncated O-glycan, that is commonly noticed in colorectal cancer (CRC). It is usually expressed at high levels in cancer cells. Tn antigen is small in size and simple in structure. It has a non-physiological glycan structure in humans, hence it may be identified as foreign by the immune system. | | Biochem/physiol Actions | Tn antigen stimulates colorectal cancer metastasis through the activation of epithelial-mesenchymal transition, mediated by H-Ras. It acts as a precursor to several significant complex O-glycans. Subpopulations of blood cells in all lineages carrying the Tn antigen results in a hematological disorder called Tn syndrome. |
| TN ANTIGEN Preparation Products And Raw materials |
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