6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide

6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide
  • CAS No.:67287-54-1
Other grades of this product :
6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Basic information
Product Name:6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide
Synonyms:6-Chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide;(±)-SKF 82526 HydrobroMide;6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol HydrobroMide;SKF 82526 HydrobroMide;6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide;FENOLDOPAM MONOHYDROBROMIDE;6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1h-3-benzazepine-7,8-diol monohydrobromide;FenoldopaM HydrobroMide
CAS:67287-54-1
MF:C16H16ClNO3.BrH
MW:386.67
EINECS:266-634-7
Product Categories:Agonists;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals
Mol File:67287-54-1.mol
6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Chemical Properties
Melting point >233°C (dec.)
storage temp. 2-8°C
solubility DMSO: >12mg/mL
form Solid
color off-white
Safety Information
Hazard Codes Xn
Risk Statements 22-36-42/43
Safety Statements 22-26-36/37/39
WGK Germany 3
MSDS Information
6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Usage And Synthesis
UsesDopamine D1-receptor agonist. Antihypertensive.
UsesFenoldopam Monohydrobromide is a potent D-1 dopamine agonists.
Biochem/physiol ActionsFenoldopam is a selective dopamine agonist that is being considered for the parenteral treatment of systemic hypertension. In both an oral and parenteral form, fenoldopam causes peripheral vasodilation by stimulating dopamine-1 adrenergic receptors. Intravenous fenoldopam may provide advantages over sodium nitroprusside because it can induce both a diuresis and natriuresis, is not light sensitive, and is not associated with cyanide toxicity. There is no evidence for rebound hypertension after discontinuation of fenoldopam infusion.
6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Preparation Products And Raw materials

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