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| 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Basic information |
| Product Name: | 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide | | Synonyms: | 6-Chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide;(±)-SKF 82526 HydrobroMide;6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol HydrobroMide;SKF 82526 HydrobroMide;6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide;FENOLDOPAM MONOHYDROBROMIDE;6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1h-3-benzazepine-7,8-diol monohydrobromide;FenoldopaM HydrobroMide | | CAS: | 67287-54-1 | | MF: | C16H16ClNO3.BrH | | MW: | 386.67 | | EINECS: | 266-634-7 | | Product Categories: | Agonists;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals | | Mol File: | 67287-54-1.mol |
| 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Chemical Properties |
| Melting point | >233°C (dec.) | | storage temp. | 2-8°C | | solubility | DMSO: >12mg/mL | | form | Solid | | color | off-white |
| 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Usage And Synthesis |
| Uses | Dopamine D1-receptor agonist. Antihypertensive. | | Uses | Fenoldopam Monohydrobromide is a potent D-1 dopamine agonists. | | Biochem/physiol Actions | Fenoldopam is a selective dopamine agonist that is being considered for the parenteral treatment of systemic hypertension. In both an oral and parenteral form, fenoldopam causes peripheral vasodilation by stimulating dopamine-1 adrenergic receptors. Intravenous fenoldopam may provide advantages over sodium nitroprusside because it can induce both a diuresis and natriuresis, is not light sensitive, and is not associated with cyanide toxicity. There is no evidence for rebound hypertension after discontinuation of fenoldopam infusion. |
| 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Preparation Products And Raw materials |
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