Other grades of this product :
| FURIN INHIBITOR II Basic information |
| Product Name: | FURIN INHIBITOR II | | Synonyms: | HEXA-D-ARGININE;H-(D)RRRRRR-NH2;FURIN INHIBITOR II;H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2;Hexa-D-arginine aMide;D-ArgininamideD-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-alanine;Furin Inhibitor II, >98%;Hexa-D-arginine,RRRRRR | | CAS: | 673202-67-0 | | MF: | C36H75N25O6 | | MW: | 954.14 | | EINECS: | | Product Categories: | | Mol File: | 673202-67-0.mol |
| FURIN INHIBITOR II Chemical Properties |
| density | 1.59±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C | | form | lyophilized | | pka | 13.24±0.46(Predicted) |
| FURIN INHIBITOR II Usage And Synthesis |
| Uses | Furin Inhibitor II has been used as a furin inhibitor: - to study its effects on transforming growth factor β1 (TGF-β1) induced glial cell line-derived neurotrophic factor (GDNF) production in non-tumorigenic immortalized human granulosa cell line (SVOG).
- to study its effect on cleavage of (Pro) renin receptor (PRR) induced by bovine serum albumin (BSA) in human kidney 2 (HK-2) cells.
- in furin cleavage assay.
| | General Description | Furin is a calcium-dependent serine endoproteinase and belongs to the subtilisin-like proprotein/prohormone convertase (PC) family. It is distributed ubiquitously and has a rhythmic movement between the trans-Golgi network, cell surface and the endosomes. | | Biochem/physiol Actions | Furin plays a role in processing several pro-proteins such as, bone morphogenetic protein?4 (BMP-4), insulin receptor and Notch1 receptor. It also processes human immune deficiency virus 1 (HIV-1) glycoprotein gp160, several metalloproteases?and pro-β-nerve growth (pro-β-NGF) factor. Furin is also involved in cleaving transforming growth factor β1 (TGF-β1). |
| FURIN INHIBITOR II Preparation Products And Raw materials |
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