N-OMEGA-ACETYLHISTAMINE

CAS No.：673-49-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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N-OMEGA-ACETYLHISTAMINE Basic information

Product Name:	N-OMEGA-ACETYLHISTAMINE
Synonyms:	n-acetylhistamine;N-OMEGA-ACETYLHISTAMINE;N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE;N-(2-(imidazol-4-yl)ethyl)acetamide;N-w-Acetylhistamine;N-[2-(1H-imidazol-5-yl)ethyl]acetamide;N-[2-(3H-Imidazole-4-yl)ethyl]acetamide;N-omega-Acetylhistamine,98%
CAS:	673-49-4
MF:	C7H11N3O
MW:	153.18
EINECS:	211-610-3
Product Categories:	Building Blocks;Heterocyclic Building Blocks;Imidazoles
Mol File:	673-49-4.mol

N-OMEGA-ACETYLHISTAMINE Chemical Properties

Melting point	147-149 °C(lit.)
Boiling point	276.1°C (rough estimate)
density	1.1648 (rough estimate)
refractive index	1.5860 (estimate)
storage temp.	0-6°C
solubility	DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
form	Solid
pka	14.42±0.10(Predicted)
color	White to Off-White

Safety Information

Safety Statements	24/25
WGK Germany	3

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

N-OMEGA-ACETYLHISTAMINE Usage And Synthesis

Chemical Properties	White to slightly yellow-cream crystalline powder
Uses	Acetylhistamine, is a histamine metabolite, and can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions.
Definition	ChEBI: A member of the class of acetamides that is acetamide comprising histamine having an acetyl group attached to the side-chain amino function.

N-OMEGA-ACETYLHISTAMINE Preparation Products And Raw materials

Raw materials

Hydrochloric acid-->Tetrahydrofuran-->Thionyl chloride-->Sodium carbonate-->Acetic anhydride-->Ammonium hydroxide-->Benzene-->Lithium Aluminum Hydride-->Formaldehyde-->POTASSIUM CYANIDE-->Copper(II) sulfate-->Hydrogen Sulfide-->PICRIC ACID-->D(-)-Fructose

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