NORVERAPAMIL HYDROCHLORIDE

NORVERAPAMIL HYDROCHLORIDE
  • CAS No.:67812-42-4
Other grades of this product :
NORVERAPAMIL HYDROCHLORIDE Basic information
Product Name:NORVERAPAMIL HYDROCHLORIDE
Synonyms:NORVERAPAMIL HCL;NORVERAPAMIL HYDROCHLORIDE;(+/-)-VERAPAMIL, NOR-METHYL-, HYDROCHLORIDE;a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitril;n-nor-(±)-verapamil hydrochloride;α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)- benzeneacetonitrile;(+-)-VERAPAMIL HYDROCHLORIDE, NOR-METHYL (NORVERAPAMIL HYDROCH;a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile
CAS:67812-42-4
MF:C26H37ClN2O4
MW:477.04
EINECS:
Product Categories:Metabolites;Various Metabolites and Impurities
Mol File:67812-42-4.mol
NORVERAPAMIL HYDROCHLORIDE Chemical Properties
Melting point softens at 50°C, 155-160°C dec.
Fp 9℃
storage temp. desiccated
solubility H2O: >10 mg/mL
form solid
color white
Stability:Hygroscopic
EPA Substance Registry SystemBenzeneacetonitrile, .alpha.-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)-, hydrochloride (1:1) (67812-42-4)
Safety Information
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
NORVERAPAMIL HYDROCHLORIDE Usage And Synthesis
Chemical PropertiesOff-White Crystalline Solid
UsesA metabolite of Verapamil
UsesNor Verapamil Hydrochloride (Verapamil EP Impurity J HCl) is a metabolite of Verapamil.
General DescriptionNorverapamil is a primary urinary metabolite of verapamil, a calcium channel blocker used in the treatment of hypertension, angina pectoris, and cardiac arrhythmia. Verapamil is also an effective preventive medication for migraines. This Certified Reference Material is applicable for use as starting material in calibrators or controls for verapamil testing methods by LC-MS/MS or GC-MS.
Biochem/physiol ActionsNorverapamil is an N-demethylated metabolite of verapamil. It has significantly less calcium channel blocking ability and exhibit therapeutic activity.
NORVERAPAMIL HYDROCHLORIDE Preparation Products And Raw materials

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