Other grades of this product :
| Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Basic information |
| Product Name: | Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 | | Synonyms: | N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-t-butyl-glycine-L-alanine 2-aminoethyl amide;TAPI-2 acetate salt;Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2;N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)- | | CAS: | 689284-12-6 | | MF: | C19H37N5O5 | | MW: | 415.53 | | EINECS: | | Product Categories: | | Mol File: | 689284-12-6.mol |
| Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Chemical Properties |
| storage temp. | -20°C | | form | lyophilized solid | | color | white to off-white |
| Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Usage And Synthesis |
| Uses | TAPI 2 is a matrix metalloprotease (MMP) inhibitor, which inhibits merpin α and β homo-oligomers. | | Biochem/physiol Actions | TAPI-2 is a potent inhibitor matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase). It blocks the shedding of several cell surface proteins such as β-amyloid precursor protein, inhibits TNF-α release as well as a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands. TAPI-2 is considered a fairly broad metalloproteinase inhibitor, but it much more selective for TACE than GM6001. |
| Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye