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| 2'-HYDROXY-6'-METHOXYACETOPHENONE Basic information |
| 2'-HYDROXY-6'-METHOXYACETOPHENONE Chemical Properties |
| Melting point | 58-60 °C(lit.) | | Boiling point | 141 °C16 mm Hg(lit.) | | density | 1.158 | | refractive index | 1.5500 (estimate) | | Fp | 141°C/16mm | | storage temp. | Sealed in dry,Room Temperature | | pka | 9.79±0.10(Predicted) | | BRN | 1869049 | | CAS DataBase Reference | 703-23-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | Hazard Note | Irritant | | TSCA | N | | HS Code | 29145090 |
| 2'-HYDROXY-6'-METHOXYACETOPHENONE Usage And Synthesis |
| Chemical Properties | Yellow crystalline powder | | Uses | 2''-Hydroxy-6''-methoxyacetophenone is useful in the synthesis of an aminopyrazole compound which is used to treat cancer and inhibits Chk1. 2''-Hydroxy-6''-methoxyacetophenone is also used to prepare 5,?4''-?disubstituted flavones, predicted androgen receptor antagonists and naphthopyrazolyl carbothioamides which are anticancer agents. | | Uses | 2′-Hydroxy-6′-methoxyacetophenone was used as starting material in the synthesis of 5-methoxyflavaone. It was also used in synthesis of 5,6-dihydroxyflavone. | | Preparation | Preparation by reaction of methyl iodide on 2,6-dihydroxyacetophenone with potassium carbonate in boiling acetone (56%). | | General Description | An organometallic synthetic route to 2′-hydroxy-6′-methoxyacetophenone was reported. |
| 2'-HYDROXY-6'-METHOXYACETOPHENONE Preparation Products And Raw materials |
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