Product

1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one

CAS No.：70351-51-8

Other grades of this product :

1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one Basic information

Product Name:	1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one
Synonyms:	1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one;Supercinnamaldehyde;2H-Indol-2-one, 1,3-dihydro-1-methyl-3-(2-oxopropylidene)-
CAS:	70351-51-8
MF:	C12H11NO2
MW:	201.22
EINECS:
Product Categories:
Mol File:	70351-51-8.mol

1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one Chemical Properties

storage temp.	2-8°C
solubility	DMSO: soluble10mg/mL, clear
form	powder
color	faint red to very dark red

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38-52/53
Safety Statements	26-36/37-61
WGK Germany	3

MSDS Information

1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one Usage And Synthesis

Uses

Supercinnamaldehyde may be used in transient receptor potential ankyrin 1 (TRPA 1)-mediated cell signaling studies.

Biochem/physiol Actions

Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC50 = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.

1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one Preparation Products And Raw materials

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