Product

5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE

CAS No.：70978-54-0

Other grades of this product :

5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE Basic information

Product Name:	5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE
Synonyms:	1-(5-BROMO-2-HYDROXY-3-NITROPHENYL)ETHANONE;3-BROMO-6-HYDROXY-5-NITRO ACETOPHENONE;5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE;5-BROMO-2-HYDROXY-3-NITROACETOPHENONE;JRH-01018, 1-(5-Bromo-2-hydroxy-3-nitrophenyl)ethanone, 97%;5'-Bromo-2'-hydroxy-3'-nitroacetophenone >Ethanone, 1-(5-bromo-2-hydroxy-3-nitrophenyl)-;1-(5-Bromo-2-hydroxy-3-nitrophenyl)ethan-1-one
CAS:	70978-54-0
MF:	C8H6BrNO4
MW:	260.04
EINECS:
Product Categories:	Aromatic Acetophenones & Derivatives (substituted);Building Blocks;C7 to C8;Carbonyl Compounds;Chemical Synthesis;Ketones;Organic Building Blocks
Mol File:	70978-54-0.mol

5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE Chemical Properties

Melting point	129-132 °C(lit.)
Boiling point	272.9℃
density	1.763
Fp	118.9℃
storage temp.	Sealed in dry,Room Temperature
form	powder to crystal
pka	6.47±0.38(Predicted)
color	Light yellow to Yellow to Orange
CAS DataBase Reference	70978-54-0(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	29145090

MSDS Information

Provider	Language
SigmaAldrich	English

5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE Usage And Synthesis

Uses	5'-Bromo-2'-hydroxy-3'-nitroacetophenone is used as a chemical reagent in the synthesis of amides and benzoxazoles directly using a sulfate catalyst and microwaves. 1-(5-Bromo-2-hydroxy-3-nitrophen yl)ethanone is used in studies involving HIV-1 integrase inhibitors.
Preparation	Preparation by nitration of 5-bromo-2-hydroxyacetophenone in refluxing carbon tetrachloride (88%).

5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE Preparation Products And Raw materials

Raw materials

5-Bromo-2-hydroxyacetophenone

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