GSK-3 Inhibitor X

CAS No.：740841-15-0

Other grades of this product :

GSK-3 Inhibitor X Basic information

Product Name:	GSK-3 Inhibitor X
Synonyms:	GSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem;2H-Indol-2-one, 3-[3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-
CAS:	740841-15-0
MF:	C18H12BrN3O3
MW:	398.21
EINECS:
Product Categories:	Other Enzyme Inhibitors and Activators.
Mol File:	740841-15-0.mol

GSK-3 Inhibitor X Chemical Properties

storage temp.	+2C to +8C
form	Dark purple solid
Sensitive	Light Sensitive

Safety Information

MSDS Information

GSK-3 Inhibitor X Usage And Synthesis

General Description	An acetoxime analog of BIO, GSK-3 Inhibitor IX (Cat. No. 361550) that exhibits greater selectivity for GSK-3α/β (IC₅₀ = 10 nM) over Cdk5/p25, Cdk2/cyclin A, and Cdk1/cyclin B (IC₅₀ = 2.4 μM, 4.3 μM, and 63 μM, respectively). A weak inhibitor of Cdk4/cyclin D1 and many other non-related kinases (IC₅₀ ≥ 10 μM). Yields BIO (Cat. No. 361550) upon hydrolysis.
Biochem/physiol Actions	Product does not compete with ATP.

GSK-3 Inhibitor X Preparation Products And Raw materials

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