Other grades of this product :
| PAF (C18) Basic information |
| Product Name: | PAF (C18) | | Synonyms: | PAF (C18);PLATELET ACTIVATING FACTOR-18;PLATELET ACTIVATING FACTOR (C18);1-o-octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine;1-o-stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine;L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-ACETYL-GAMMA-O-OCTADECYL;C18-02:0 PC;C18 PAF | | CAS: | 74389-69-8 | | MF: | C28H58NO7P | | MW: | 551.74 | | EINECS: | | Product Categories: | | Mol File: | 74389-69-8.mol |
| PAF (C18) Chemical Properties |
| storage temp. | -20°C | | solubility | chloroform: 10 mg/mL |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29310099 |
| PAF (C18) Usage And Synthesis |
| Chemical Properties | white solid | | Uses | C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine is suitable as a substrate for enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. | | Uses | C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. | | Definition | ChEBI: 2-acyl-1-alkyl-sn-glycero-3-phosphocholine betaine in which the 1-alkyl and 2-acyl groups are specified as octacdecyl and acetyl respectively | | General Description | C18-02:0 PC, also known as 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18∶0-PAF), is a platelet-activating factor lipid. It belongs to a class of natural PAFs and is produced in basophil leucocytes, macrophages, polymorphonuclear neutrophils and monocytes and platelets. | | Biochem/physiol Actions | C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18-PAF), a platelet-activating factor (PAF) facilitates platelet aggregation and secretion. It also plays a key role in inflammation and anaphylaxis. C18-PAF exhibits neurotoxic effects by initiating caspase-independent death in PAF receptor-deficient neurons. |
| PAF (C18) Preparation Products And Raw materials |
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