N-LAUROYL-D-ERYTHRO-SPHINGOSINE

CAS No.：74713-60-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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N-LAUROYL-D-ERYTHRO-SPHINGOSINE Basic information

Product Name:	N-LAUROYL-D-ERYTHRO-SPHINGOSINE
Synonyms:	N-LAUROYL-D-ERYTHRO-SPHINGOSINE;N-LAUROYL-D-SPHINGOSINE;C12 CERAMIDE;C12-D-ERYTHRO-SPHINGOSINE;CERAMIDE C12;N-lauroylsphingosine;N-LAUROYL-D-ERYTHRO-SPHINGOSINE, 99+%, SYNTHETICAL;N-Lauroyl-D-erythro-sphingosineCeramide C12
CAS:	74713-60-3
MF:	C30H59NO3
MW:	481.79
EINECS:
Product Categories:	Amines;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	74713-60-3.mol

N-LAUROYL-D-ERYTHRO-SPHINGOSINE Chemical Properties

Melting point	70 - 72°C
Boiling point	579.38°C (rough estimate)
density	0.9777 (rough estimate)
refractive index	1.6310 (estimate)
storage temp.	-20°C
solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated, Sonicat
form	Solid
color	White to Off-White
BRN	1717021

Safety Information

Safety Statements	24/25
WGK Germany	3

MSDS Information

Provider	Language
ACROS	English

N-LAUROYL-D-ERYTHRO-SPHINGOSINE Usage And Synthesis

Chemical Properties	white powder
Uses	Ceramide is one of the simplest sphingolipids, consisting of a sphingosine base N-linked to a fatty acid, and is a membrane mediator for cell-signaling events. N-Acyl chain length of membrane ceramides can influence bidimensional transitions, condensed domain morphology, and interfacial thickness.
Uses	C12 Ceramide (d18:1/12:0) or N-lauroyl-D-erythro-sphingosine has been used: as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions as an internal standard for lipid extraction in U87MG (human glioma cell line) as an internal standard for the quantification of ceramide using liquid chromatography-mass spectrometry (LC-MS) in rat tissues
General Description	Ceramide is a sphingolipid with long acyl chain attached to a fatty. It is synthesized in the endoplasmic reticulum by ceramide synthase.
Biochem/physiol Actions	Ceramides?are signaling sphingolipids, which are implicated in regulating stress responses and inflammation. It also regulates cell growth arrest, differentiation and apoptosis.

N-LAUROYL-D-ERYTHRO-SPHINGOSINE Preparation Products And Raw materials

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