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| 7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE Basic information |
| Product Name: | 7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE | | Synonyms: | 7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE;4',7,8-Trihydroxy isoflavone;7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE 98%;YN1;7,8-dihydroxy-3-(4-hydroxyphenyl)-4h-chroMen-4-one;4H-1-Benzopyran-4-one,7,8-dihydroxy-3-(4-hydroxyphenyl)-;YN1 >=98% (HPLC);7,8-Dihydroxy-3-(4-hydroxy-pheny | | CAS: | 75187-63-2 | | MF: | C15H10O5 | | MW: | 270.24 | | EINECS: | | Product Categories: | | Mol File: | 75187-63-2.mol |
| 7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: soluble10mg/mL, clear | | form | powder | | color | white to beige |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | HS Code | 2932990090 |
| 7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE Usage And Synthesis |
| Biochem/physiol Actions | YN1 is a potent inhibitor of PFKFB3 (6-Phosphfructo-2-kinase/fructose-2,6-bisphosphatase: IC50 = 670 nM). PFKFB3 is over expressed in many cancers, and catalyzes the production of fructose-2,6-bisphosphate, which can potentiate PFK1 activity, enhancing glycolysis in tumor cells. YN1 inhibits glycolysis and proliferation in HeLa cells. |
| 7,8-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE Preparation Products And Raw materials |
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