Diethyl malate

Diethyl malate
  • CAS No.:7554-12-3
Other grades of this product :
Diethyl malate Basic information
Product Name:Diethyl malate
Synonyms:2-hydroxy-butanedioicaciddiethylester;Butanedioicacid,hydroxy-,diethylester;hydroxy-butanedioicacidiethylester;FEMA 2374;ETHYL-DL-MALATE;DIETHYL MALATE;DIETHYL DL-MALATE;DL-MALIC ACID DIETHYL ESTER
CAS:7554-12-3
MF:C8H14O5
MW:190.19
EINECS:231-444-5
Product Categories:
Mol File:7554-12-3.mol
Diethyl malate Chemical Properties
Boiling point 122-124 °C12 mm Hg(lit.)
density 1.128 g/mL at 25 °C(lit.)
refractive index 1.4330 to 1.4360
FEMA 2374 | DIETHYL MALATE
Fp 185 °F
storage temp. Sealed in dry,Room Temperature
pka12.35±0.20(Predicted)
form clear liquid
color Colorless to Light yellow
JECFA Number620
EPA Substance Registry SystemButanedioic acid, hydroxy-, diethyl ester (7554-12-3)
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
Diethyl malate Usage And Synthesis
Chemical PropertiesDiethyl malate has a fruity odor with a pleasant herbaceous undertone. It is an ester of dicarboxylic acid
OccurrenceIt exhibits two optically active isomers in addition to the optically inactive form; the most common is the l-isomer; reported present in the cultures of certain fungi (Rhizopus). Reported found in raspberry, cognac, malt whiskey, cider, sherry, white, red, port, sparkling, rose, strawberry and bilberry wines
UsesDiethyl DL-Malate is used as a reagent in the synthesis of dicarboxylic nitroxyalkylamides and nitroxyalkylimides as anti-ischemic agents.
PreparationThe l-isomer can be prepared by esterification of the l-isomer of the acid with alcohol in the presence of HCl.
Synthesis Reference(s)Synthesis, p. 138, 1982 DOI: 10.1055/s-1982-29718
Diethyl malate Preparation Products And Raw materials
Raw materialsL-Malic acid-->YSAVZVORKRDODB-UHFFFAOYSA-N-->Diethyl fumarate-->Water-->Levulinic acid-->Ethanol-->2-Methyltetrahydrofuran-->DL-Malic acid-->Furfural

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