5-AMINO-2-METHYLINDOLE

CAS No.：7570-49-2

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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5-AMINO-2-METHYLINDOLE Basic information

Product Name:	5-AMINO-2-METHYLINDOLE
Synonyms:	2-METHYL-1H-INDOL-5-AMINE;5-AMINO-2-METHYLINDOLE;5-AMINO-2-METHYLINDOL 97%;5-Amino-2-methylindole 95%;5-Amino-2-methylindole,95%;5-Amino-2-methylindole,98%;2-Methylindol-5-ylamine;5-Amino-2-methyl-1H-indole 95%
CAS:	7570-49-2
MF:	C9H10N2
MW:	146.19
EINECS:
Product Categories:	Building Blocks;C7 to C9;Indoles;Simple Indoles;Chemical Synthesis;Heterocyclic Building Blocks;Indole;Building Blocks;Heterocyclic Building Blocks
Mol File:	7570-49-2.mol

5-AMINO-2-METHYLINDOLE Chemical Properties

Melting point	153-157 °C(lit.)
Boiling point	255.81°C (rough estimate)
density	1.0976 (rough estimate)
refractive index	1.5600 (estimate)
storage temp.	Keep in dark place,Sealed in dry,2-8°C
pka	17.97±0.30(Predicted)
form	powder to crystal
color	Red to Dark blue to Black
Sensitive	Stench
CAS DataBase Reference	7570-49-2(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
Hazard Note	Harmful/Stench
HS Code	2933998090

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English
ALFA	English

5-AMINO-2-METHYLINDOLE Usage And Synthesis

Chemical Properties	brown crystalline powder or chunks
Uses	Reactant for preparation of:• ;Cytotoxic and antimitotic agents1• ;Potential antimicrobial aminoketones2• ;Inhibitors of monoamine oxidase (MAO)3• ;Protein kinase c theta (PKCθ) inhibitors4• ;Factor Xa inhibitors5• ;Inhibitors of vascular endothelial growth factor type 2 (VEGFR-2)6• ;Demethylasterriquinone B1receptor ligands7
Uses	Reactant for preparation of: Cytotoxic and antimitotic agents Potential antimicrobial aminoketones Inhibitors of monoamine oxidase (MAO) Protein kinase c theta (PKCθ) inhibitors Factor Xa inhibitors Inhibitors of vascular endothelial growth factor type 2 (VEGFR-2) Demethylasterriquinone B1receptor ligands

5-AMINO-2-METHYLINDOLE Preparation Products And Raw materials

Raw materials

2-METHYL-5-NITROINDOLE-->2-Iodo-1,4-benzenediamine-->2-METHYL-5-NITROINDOLINE-->2-Iodo-4-nitroaniline-->2-Methylindole

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