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| Tris(3-hydroxypropyltriazolylMethyl)aMine 95% Basic information |
| Product Name: | Tris(3-hydroxypropyltriazolylMethyl)aMine 95% | | Synonyms: | Tris(3-hydroxypropyltriazolylMethyl)aMine 95%;3,3′,3′′-(4,4′,4′′-(Nitrilotris(methylene))tris(1H-1,2,3-triazole-4,1-diyl))tris(propan-1-ol);THPTA;Tris(3-hydroxypropyltriazolylmethyl)amine;4,4',4''-Nitrilotris(4-(1H-1,2,3-triazol-4-yl)butan-1-ol);3,3',3''-((4,4'4,”-nitrilotris(methylene))tris(1H-1,2,3-triazole-5,1-diyl))tris(propan-1-ol) -(THPTA);Tris(3-hydroxypropyltriazolylMethyl)aMine95%;tris(3-hydroxypropyltriazolymethyl)amine | | CAS: | 760952-88-3 | | MF: | C18H30N10O3 | | MW: | 434.51 | | EINECS: | | Product Categories: | | Mol File: | 760952-88-3.mol |
| Tris(3-hydroxypropyltriazolylMethyl)aMine 95% Chemical Properties |
| Melting point | 331-336°C (decomposition) | | Boiling point | 723.8±70.0 °C(Predicted) | | density | 1.44±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Very Slightly) | | form | Solid | | pka | 14.34±0.10(Predicted) | | color | White to Off-White |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 |
| Tris(3-hydroxypropyltriazolylMethyl)aMine 95% Usage And Synthesis |
| Description | THPTA is a water-soluble, very effective ligand for Cu(I)-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). It serves a dual purpose: 1) Acceleration of the CuAAC reaction by maintaining the Cu(I) oxidation state of copper sources and 2) Protection of biomolecules from oxidative damage during the labeling reaction.
THPTA is a superior alternative to water-insoluble TBTA.
a) J. Am. Chem. Soc. 2011, 133, 17993.
b) Bioconjugate Chem. 2010, 21, 1912. | | Uses | Tris(3-hydroxypropyltriazolylmethyl)amine when complexed to copper(I) can be used as a catalyst. |
| Tris(3-hydroxypropyltriazolylMethyl)aMine 95% Preparation Products And Raw materials |
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