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| DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID Basic information |
| DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID Chemical Properties |
| Melting point | 238-245oC | | Boiling point | 482.1±55.0 °C(Predicted) | | density | 1.529±0.06 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | NH4OH 1 M: 50 mg/mL, clear, colorless | | form | solid | | pka | 2.46±0.10(Predicted) | | color | white | | BRN | 2446389 | | CAS DataBase Reference | 76326-31-3(CAS DataBase Reference) |
| DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID Usage And Synthesis |
| Uses | DL-2-Amino-5-phosphonopentanoic acid has been used:- in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses
- used in growth medium for inhibition of electrical activity in the neuronal network
- used to isolate N-methyl-D-aspartate receptors (NMDAR) or α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)-mediated currents were isolated using this product
- used in double distilled water to compare its NMDA antagonistic action with that of prion protein (PrPC)
| | Definition | ChEBI: The 5-phosphono derivative of 2-aminopentanoic acid; acts as an N-methyl-D-aspartate receptor antagonist. | | Biological Activity | Potent NMDA antagonist. See separate isomers (D-(-)-2-Amino-5-phosphonopentanoic acid and L-(+)-2-Amino-5-phosphonopentanoic acid ). | | Biochem/physiol Actions | Anticonvulsant; potent and selective NMDA receptor antagonist. |
| DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID Preparation Products And Raw materials |
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