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| 4-BROMO-A23187 Basic information |
| Product Name: | 4-BROMO-A23187 | | Synonyms: | A23187, 4-Bromo- - CAS 76455-48-6 - Calbiochem;ANTIBIOTIC A-23187, 4-BROMO;CALCIMYCIN, 4-BROMO;4-BROMO-A23187;4-BROMO-ANTIBIOTIC;4-BROMO-ANTIBIOTIC A23187;4-BROMOCALCIMYCIN;4-BROMOCALCIMYCIN A23187 | | CAS: | 76455-48-6 | | MF: | C29H36BrN3O6 | | MW: | 602.52 | | EINECS: | | Product Categories: | | Mol File: | 76455-48-6.mol |
| 4-BROMO-A23187 Chemical Properties |
| storage temp. | 2-8°C | | solubility | ethanol: 20 mg/mL | | form | powder | | color | yellow |
| 4-BROMO-A23187 Usage And Synthesis |
| Chemical Properties | Yellow powder | | Uses | 4-Bromo-calcium Ionophore A23187 has been used for the activation of Ca2+/calmodulin kinase II (CaMKII) in HeLa cell line. It has also been used as a calcium mobilizer to investigate its effect on superoxide dismutase 1 (SOD1) aggregates in VSC 4.1 cells. | | Uses | 4-Bromo-A23187 is an ionophore that transports Zn2+ and Mn2+ with high selectivity over Ca2+. | | Biochem/physiol Actions | 4-Bromo-calcium Ionophore A23187 is a modulator of apoptosis. It inhibits apoptosis in a concentration dependent manner in neutrophils which are aging in vitro and increases the intracellular Ca2+ levels. |
| 4-BROMO-A23187 Preparation Products And Raw materials |
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