4-BROMO-A23187

4-BROMO-A23187
  • CAS No.:76455-48-6
Other grades of this product :
4-BROMO-A23187 Basic information
Product Name:4-BROMO-A23187
Synonyms:A23187, 4-Bromo- - CAS 76455-48-6 - Calbiochem;ANTIBIOTIC A-23187, 4-BROMO;CALCIMYCIN, 4-BROMO;4-BROMO-A23187;4-BROMO-ANTIBIOTIC;4-BROMO-ANTIBIOTIC A23187;4-BROMOCALCIMYCIN;4-BROMOCALCIMYCIN A23187
CAS:76455-48-6
MF:C29H36BrN3O6
MW:602.52
EINECS:
Product Categories:
Mol File:76455-48-6.mol
4-BROMO-A23187 Chemical Properties
storage temp. 2-8°C
solubility ethanol: 20 mg/mL
form powder
color yellow
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36/37/39-36/37
WGK Germany 3
HS Code 29419090
MSDS Information
ProviderLanguage
SigmaAldrich English
4-BROMO-A23187 Usage And Synthesis
Chemical PropertiesYellow powder
Uses4-Bromo-calcium Ionophore A23187 has been used for the activation of Ca2+/calmodulin kinase II (CaMKII) in HeLa cell line. It has also been used as a calcium mobilizer to investigate its effect on superoxide dismutase 1 (SOD1) aggregates in VSC 4.1 cells.
Uses4-Bromo-A23187 is an ionophore that transports Zn2+ and Mn2+ with high selectivity over Ca2+.
Biochem/physiol Actions4-Bromo-calcium Ionophore A23187 is a modulator of apoptosis. It inhibits apoptosis in a concentration dependent manner in neutrophils which are aging in vitro and increases the intracellular Ca2+ levels.
4-BROMO-A23187 Preparation Products And Raw materials

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