1-(3-AMINOPROPYL)-2-PYRROLIDINONE

CAS No.：7663-77-6

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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1-(3-AMINOPROPYL)-2-PYRROLIDINONE Basic information

Product Name:	1-(3-AMINOPROPYL)-2-PYRROLIDINONE
Synonyms:	1-(3-AMINOPROPYL)-2-PYRROLIDONE;RARECHEM AL BW 2176;N-(3'-AMINOPROPYL)-2-PYRROLIDINONE;N-(3'-AMINOPROPYL)-2-PYRROLIDONE;1-(3-aminopropyl)-2-pyrrolidinon;2-Pyrrolidinone, 1-(3-aminopropyl)-;N-(3-aminopropyl)pyrrolidin-2-one;3-(2-oxo-1-pyrrolidinyl)propylammonium
CAS:	7663-77-6
MF:	C7H14N2O
MW:	142.2
EINECS:	231-632-7
Product Categories:	Building Blocks;C4 to C8;Amines;Heterocycles;Chemical Synthesis;Heterocyclic Building Blocks;Miscellaneous Reagents;Synthetic Intermediates;Building Blocks;Heterocyclic Building Blocks;Pyrrolidines;Intermediates
Mol File:	7663-77-6.mol

1-(3-AMINOPROPYL)-2-PYRROLIDINONE Chemical Properties

Boiling point	120-123 °C1 mm Hg(lit.)
density	1.014 g/mL at 25 °C(lit.)
refractive index	n20/D 1.5(lit.)
Fp	>230 °F
storage temp.	Keep in dark place,Sealed in dry,2-8°C
form	Liquid
pka	9.85±0.10(Predicted)
Specific Gravity	1.01
color	Clear colorless to slightly brown
CAS DataBase Reference	7663-77-6(CAS DataBase Reference)

Safety Information

Hazard Codes	C,Xi
Risk Statements	34
Safety Statements	26-27-36/37/39-45
RIDADR	UN 3267 8/PG 2
WGK Germany	3
RTECS	UY5739500
F	9-34
Hazard Note	Irritant
HS Code	29337900

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

1-(3-AMINOPROPYL)-2-PYRROLIDINONE Usage And Synthesis

Chemical Properties	Clear Slightly Yellowish Liquid
Uses	1-(3-AMinopropyl)-2-pyrrolidinone can be used as a useful synthetic intermediate.
Uses
Uses	N-(3-Aminopropyl)-2-pyrrolidinone was used in the simultaneous determination of total polyamines and three of their non?α? amino acid metabolites in urine by capillary gas-chromatographic method with nitrogen-phosphorus detection.
General Description	N-(3-Aminopropyl)-2-pyrrolidinone (PYR) conjugates (VPA-PYR) of valproic acid (VA) have been investigated for their anticonvulsant activity in mice. It is the γ-lactam form of isoputreanine.

1-(3-AMINOPROPYL)-2-PYRROLIDINONE Preparation Products And Raw materials

Raw materials

Ethyl acetate-->N,N-Dimethylformamide-->PETROLEUM ETHER-->Sodium sulfate-->Sodium hydride-->Hydrogen bromide-->Monoethanolamine-->N-Methyl-2-pyrrolidone-->2-Pyrrolidinone-->3-Bromopropylamine hydrobromide

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