1-Phenoxy-2-propanol

1-Phenoxy-2-propanol
  • CAS No.:770-35-4
Other grades of this product :
1-Phenoxy-2-propanol Basic information
Product Name:1-Phenoxy-2-propanol
Synonyms:DOWANOL? PPh;1-Phenoxy-2-propanol >=93%;DOWANOL®1-PHENOXY-2-PROPANOL;(+/-)-1-PHENOXYPROPAN-2-OL;1-PHENOXYPROPAN-2-OL;1-phenoxy-2-propano;2-Phenoxy-1-methylethanol
CAS:770-35-4
MF:C9H12O2
MW:152.19
EINECS:212-222-7
Product Categories:Benzhydrols, Benzyl & Special Alcohols
Mol File:770-35-4.mol
1-Phenoxy-2-propanol Chemical Properties
Melting point 11 °C
Boiling point 243 °C (lit.)
density 1.064 g/mL at 20 °C (lit.)
vapor pressure 1Pa at 20℃
refractive index n20/D 1.523(lit.)
Fp >230 °F
storage temp. Refrigerator
solubility water: soluble15.1g/L at 20°C
form Oil
pka14.43±0.20(Predicted)
color Clear Colourless
Specific Gravity1.051
Water Solubility 15.1g/L at 20℃
BRN 1941356
Stability:Stable. Flammable. Incompatible with strong oxidizing agents.
LogP1.41 at 24.1℃
CAS DataBase Reference770-35-4(CAS DataBase Reference)
NIST Chemistry Reference1-Phenoxy-2-propanol(770-35-4)
EPA Substance Registry System1-Phenoxy-2-propanol (770-35-4)
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 23-26
WGK Germany 1
RTECS UB8886500
TSCA Yes
HS Code 29094990
Hazardous Substances Data770-35-4(Hazardous Substances Data)
ToxicityLD50 orl-rat: 2830 mg/kg NTIS** OTS0539745
MSDS Information
ProviderLanguage
Propylene glycol phenyl ether English
ACROS English
SigmaAldrich English
ALFA English
1-Phenoxy-2-propanol Usage And Synthesis
Chemical Propertiescolourless liquid
UsesHigh-boiling solvent, bactericidal agent, fixa- tive for soaps and perfumes, intermediate for plas- ticizers.
Uses1-Phenoxy-2-propanol is a useful synthetic intermediate. It was used in the preparation of acylarylthiocarbamates as nonnucleoside reverse transcriptase inhibitors.
DefinitionColorless liquid.Combustible.
Synthesis Reference(s)Tetrahedron Letters, 36, p. 9357, 1995 DOI: 10.1016/0040-4039(95)02027-M
General Description1-Phenoxy-2-propanol (PP), a gycol ether, can be synthesized by reacting propylene oxide with phenol in the presence of Al2O3-MgO/Fe3O4 catalyst. The influence of its anesthetic property on gastropods has been analyzed. Its degradation by microorganisms in different soil types has been investigated.
Flammability and ExplosibilityNonflammable
Safety ProfileModerately toxic by ingestion and skin contact. Experimental reproductive effects. When heated to decompositionit emits acrid smoke and irritating vapors.
1-Phenoxy-2-propanol Preparation Products And Raw materials

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