1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE

CAS No.：77113-48-5

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE Basic information

Product Name:	1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE
Synonyms:	1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE;(5-chloro-1-pentynyl)trimethylsilylsilane;(5-Chloro-1-pentynyl)trimethylsilane;(5-chloropent-1-yn-1-yl)triMethylsilane;(5-Chloro-1-pentynyl)trimethylsilane 97%;5-chloropent-1-ynyl(trimethyl)silane;1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE, 98%1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE, 98%1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE, 98%;Silane, (5-chloro-1-pentyn-1-yl)trimethyl-
CAS:	77113-48-5
MF:	C8H15ClSi
MW:	174.74
EINECS:
Product Categories:
Mol File:	77113-48-5.mol

1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE Chemical Properties

Boiling point	75-77 °C20.6 mm Hg(lit.)
density	0.977 g/mL at 25 °C(lit.)
refractive index	n20/D 1.4560(lit.)
Fp	149 °F
Specific Gravity	0.895
Hydrolytic Sensitivity	4: no reaction with water under neutral conditions

Safety Information

Risk Statements	36/37/38
Safety Statements	23-24/25
WGK Germany	3

MSDS Information

Provider	Language
SigmaAldrich	English

1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE Usage And Synthesis

Uses	1-Chloro-5-trimethylsilyl-4-pentyne is used as an organic chemical synthesis intermediate.
Uses	(5-Chloro-1-pentynyl)trimethylsilane can be used to synthesize 5-trimethylsilyl-4-pentynyllithium (TMSPLi), which can be used as an initiator in the polymerization of styrene.

1-CHLORO-5-(TRIMETHYLSILYL)-4-PENTYNE Preparation Products And Raw materials

Raw materials

1-CHLORO-3-(TOLENE-P-SULPHONYLOXY) PROPANE-->1-CHLORO-3-IODOPROPANE-->5-Chloro-1-pentyne-->1-Bromo-3-chloropropane-->Trimethylsilyl trifluoromethanesulfonate-->Trimethylsilylacetylene-->Chlorotrimethylsilane

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