MONOETHYLGLYCINEXYLIDIDE

CAS No.：7728-40-7

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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MONOETHYLGLYCINEXYLIDIDE Basic information

Product Name:	MONOETHYLGLYCINEXYLIDIDE
Synonyms:	MONOETHYLGLYCINEXYLIDIDE;N-(2,6-DIMETHYLPHENYL)-2-(ETHYLAMINO)ACETAMIDE;Monoethyl Glycinexylidide-d6 HCl;L-86;MEGX;N-Ethylglycinexylidide;Norlidocaine;N1-(2,6-DiMethylphenyl)-2-(ethylaMino)acetaMide
CAS:	7728-40-7
MF:	C12H18N2O
MW:	206.28
EINECS:
Product Categories:	Amines, Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Amines;Aromatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:	7728-40-7.mol

MONOETHYLGLYCINEXYLIDIDE Chemical Properties

Melting point	242-245°C
Boiling point	335.6±30.0℃ (760 Torr)
density	1.047±0.06 g/cm3 (20 ºC 760 Torr)
Fp	127.8±24.7℃
storage temp.	2-8°C
solubility	H2O: soluble10mg/mL, clear
pka	pKa 8.04(H2O,t =25±0.2,I=0.01(NaCl)) (Uncertain)
form	powder
color	white to beige

Safety Information

Hazard Codes	Xn
Risk Statements	22
Safety Statements	45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
RTECS	AN7740000

MSDS Information

MONOETHYLGLYCINEXYLIDIDE Usage And Synthesis

Chemical Properties	White Solid
Uses	MEGX has been used in an approach to improve the yield of N-dealkylated lidocaine.
Uses	A metabolite of Lidocaine (L397800).
Definition	ChEBI: Amino acid amide formed from 2,6-dimethylaniline and N-ethylglycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function.
Biochem/physiol Actions	Monoethylglycinexylidide (MEGX) is an active metabolite of lidocaine.

MONOETHYLGLYCINEXYLIDIDE Preparation Products And Raw materials

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