Other grades of this product :
| Enoximone Basic information |
| Product Name: | Enoximone | | Synonyms: | ENOXIMONE;2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-(4-(methylthio)benzoyl)-;Fenoximone;MDL-17043;Pedane;Perfan;RMI-17043;4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one | | CAS: | 77671-31-9 | | MF: | C12H12N2O2S | | MW: | 248.3 | | EINECS: | | Product Categories: | APIs;API | | Mol File: | 77671-31-9.mol |
| Enoximone Chemical Properties |
| Melting point | 255-258°C | | density | 1.33 | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO: 28 mg/mL, soluble | | pka | 10.37±0.70(Predicted) | | form | solid | | color | light yellow | | CAS DataBase Reference | 77671-31-9(CAS DataBase Reference) |
| RIDADR | 3249 | | WGK Germany | 3 | | HazardClass | 6.1(b) | | PackingGroup | III |
| Enoximone Usage And Synthesis |
| Description | Enoximone is a phosphodiesterase inhibitor indicated for selective use as a
cardiostimulant in heart transplant patient maintenance. It is currently being investigated
for other indications including acute congestive heart failure. | | Originator | Merrell Dow (USA) | | Uses | Enoximone is a phosphodiesterase inhibitor used in the treatment of congestive heart failure and is selective to phosphodiesterase 3. Potent PDE-3 inhibitor. | | Brand name | Perfan IV | | Biological Activity | Inhibitor of type III phosphodiesterase (PDE3). Increases intracellular cyclic AMP (cAMP) concentrations and enhances myocardial contractility. Also induces concentration-dependent vasodilation in vitro . | | Biochem/physiol Actions | Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE. Increased cAMP results in enhanced contractility of the heart. |
| Enoximone Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye