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| (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Basic information |
| Product Name: | (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE | | Synonyms: | R(+)-8-HYDROXY-DPAT HYDROBROMIDE FULL 5- HT1A SEROTONIN;(R)-(+)-2-Dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide, (R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide;(R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide;Hydroxy-DPAT hydrobromide, (R)-(+)-8- | | CAS: | 78095-19-9 | | MF: | C16H25NO.BrH | | MW: | 328.291 | | EINECS: | | Product Categories: | | Mol File: | 78095-19-9.mol |
| (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Chemical Properties |
| storage temp. | protect from light | | solubility | H2O: >10mg/mL at ±60°C (with sonication) | | form | solid | | color | white to off-white | | optical activity | [α]25/D +68.2°, c = 1 in methanol(lit.) |
| (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Usage And Synthesis |
| Uses | (R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist: - in mice to test the activity of the serotonin receptor
- to test its effect on zebrafish melanocyte migration and survival
- to stimulate hippocampal neurons
| | Biochem/physiol Actions | (R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation. |
| (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Preparation Products And Raw materials |
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