Product

3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide

CAS No.：781652-57-1

Other grades of this product :

3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Basic information

Product Name:	3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
Synonyms:	3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide;CDPPB;mGluR5 Ligand, CDPPB;mGluR5 Ligand, CDPPB - CAS 781652-57-1 - Calbiochem;Benzamide, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)-
CAS:	781652-57-1
MF:	C23H16N4O
MW:	364.4
EINECS:
Product Categories:
Mol File:	781652-57-1.mol

3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Chemical Properties

Melting point	210-212°C
storage temp.	2-8°C
solubility	DMSO: ≥5mg/mL at warmed to 60°C
form	powder
color	white to beige

Safety Information

Hazard Codes	Xn
Risk Statements	22
WGK Germany	3

MSDS Information

3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Usage And Synthesis

Uses	3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide suppresses the incre ase of LDH release and caspase-3 activation induced by traumatic neuronal injury.
Uses	CDPPB may be used in mGluR5-mediated cell signaling studies.
Biochem/physiol Actions	CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.

3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Preparation Products And Raw materials

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