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| A-3 HYDROCHLORIDE Basic information |
| Product Name: | A-3 HYDROCHLORIDE | | Synonyms: | A-3 HYDROCHLORIDE;A-3;TRISIALYLATED, GALACTOSYLATED, TRIANTENNARY;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE;N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;1-Naphthalenesulfonamide,N-(2-aminoethyl)-5-chloro-, hydrochloride (1:1) | | CAS: | 78957-85-4 | | MF: | C12H14Cl2N2O2S | | MW: | 321.22 | | EINECS: | | Product Categories: | Protein Kinase Inhibitors and Activators;Protein Kinase | | Mol File: | 78957-85-4.mol |
| A-3 HYDROCHLORIDE Chemical Properties |
| Melting point | 173-176°C | | storage temp. | -20°C | | solubility | DMSO: 24 mg/mL | | form | solid | | color | white |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 2935909099 |
| A-3 HYDROCHLORIDE Usage And Synthesis |
| Chemical Properties | White Crystalline Solid | | Uses | Inhibits cAMP and cGMP dependent protein kinases. Also inhibits MLC kinase and protein kinase C | | Biochem/physiol Actions | Non-selective casein kinase (CK) inhibitor. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 μM), casein kinase II (Ki = 5.1 μM), myosin light chain kinase (Ki = 7.4 μM), protein kinase A (Ki = 4.3 μM), protein kinase C (Ki= 47 μM), and protein kinase G (Ki = 3.8 μM). |
| A-3 HYDROCHLORIDE Preparation Products And Raw materials |
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