![(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt)](/img/799268-73-8.jpg "(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt)")
| (S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) Basic information |
| Product Name: | (S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) |
| Synonyms: | (S)-PHOSPHORIC ACID MONO-[3-(4-BENZYLOXY-PHENYL)-2-OCTADEC-9-ENOYLAMINO-PROPYL] ESTER (AMMONIUM SALT);VPC 12249 (S);VPC 12249 (S);(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) |
| CAS: | 799268-73-8 |
| MF: | C34H55N2O6P |
| MW: | 618.8 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 799268-73-8.mol |
| (S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) Chemical Properties |
| storage temp. | -20°C |
| Safety Information |
| MSDS Information |
| (S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) Usage And Synthesis |
| Uses | VPC 12249 has been used as lysophosphatidic acid (LPA)1/3 receptor antagonist in various experimental studies. |
| General Description | VPC 12249 is an N-acyl (oleoyl) serine phosphate-based compound. |
| Biochem/physiol Actions | Lysophosphatidic acids (LPAs) are bioactive lipid mediators. It interacts with at least six specific LPA receptors (LPA1-6) to mediate extracellular signaling pathway. LPA and its receptors (LPA1-3) are implicated in the pathogenesis of radiation pneumonitis (RP). VPC 12249 (S) inhibits the binding ofLPA to LPA1 and LPA3 receptor. |
| (S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) Preparation Products And Raw materials |
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