C4, HUMAN

C4, HUMAN
  • CAS No.:80295-48-3
Other grades of this product :
C4, HUMAN Basic information
Product Name:C4, HUMAN
Synonyms:C4, HUMAN;COMPLEMENT C4;COMPLEMENT C4, HUMAN;COMPLEMENT C4 FROM HUMAN SERUM
CAS:80295-48-3
MF:
MW:0
EINECS:
Product Categories:Complement Factor ProteinsProteins and Derivatives;Complement Proteins;ComplementCell Signaling Enzymes;Plasma Protein Composition;Plasma&Blood Proteins;Plasma, Blood, and Related Proteins and Reagents
Mol File:Mol File
C4, HUMAN Chemical Properties
storage temp. −70°C
form Liquid
Safety Information
Hazard Codes B
WGK Germany 2
MSDS Information
C4, HUMAN Usage And Synthesis
UsesComplement C4 from human serum has been used in mannose binding lectin (MBL) complex assay of serum samples and in MBL-associated serine proteases based C4 activation assay of plasma samples.
General DescriptionComplement C4 is mapped to human chromosome 6p21.33. It exists in two isoforms as c4A and c4B. C4 is a 200 kDa protein belonging to α2 macroglobulin (α2M) family. It undergoes posttranslational modification like sulfation and glycosylation and finally proteolysis to become a mature protein.
Biochem/physiol ActionsVariation in the copy number of the complement C4 gene alters the complement c4A and c4B levels in age-related macular degeneration (AMD) and increases risk of developing schizophrenia.
C4, HUMAN Preparation Products And Raw materials

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