LATHOSTEROL

CAS No.：80-99-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

LATHOSTEROL Basic information

Product Name:	LATHOSTEROL
Synonyms:	3BETA-HYDROXY-5ALPHA,7-CHOLESTENE;5ALPHA-CHOLEST-7-EN-3BETA-OL;7,(5-ALPHA)-CHOLESTEN-3-BETA-OL;LATHOSTEROL;GAMMA-CHOLESTENOL;(3-beta,5-alpha)-cholest-7-en-3-o;3beta-Hydroxy-5alpha-cholest-7-ene;7-Cholesten-3-beta-ol
CAS:	80-99-9
MF:	C27H46O
MW:	386.65
EINECS:
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
Mol File:	80-99-9.mol

LATHOSTEROL Chemical Properties

Melting point	126°C
Boiling point	452.8°C (rough estimate)
density	0.9610 (rough estimate)
refractive index	1.5250 (estimate)
storage temp.	-20°C
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
form	Solid
color	White to Off-White

Safety Information

WGK Germany	3
RTECS	FZ7000000

MSDS Information

Provider	Language
SigmaAldrich	English

LATHOSTEROL Usage And Synthesis

Uses	A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.
Uses	Lathosterol has been used as a standard for the estimation of the concentrations of cholesterol and plant sterols.
Uses	5α-Cholest-7-en-3β-ol was used as a substrate in enzymatic assay for plasma cholesterol. It was used to supplement diet of Daphnia galeata to study the effect on life-history traits.
Definition	ChEBI: A cholestanoid that is (5alpha)-cholest-7-ene substituted by a beta-hydroxy group at position 3.
General Description	Lathosterol is a cholesterol synthesis precursor.
Biochem/physiol Actions	5α-Cholest-7-en-3β-ol (Lathosterol) is an intermediate in cholesterol biosynthesis pathway. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol.

LATHOSTEROL Preparation Products And Raw materials

Raw materials	Cholest-5-ene-3,7-diol, dibenzoate, (3β,7β)- (9CI)-->7BETA-HYDROXYCHOLESTEROL-->7-oxocholest-5-en-3-beta-yl acetate-->7-Dehydrocholesterol-->Cholesterol-->Ethanol
Preparation Products	Δ8(14)-Cholestenol-->(3S,5S,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873