Azidoacetic acid NHS ester

Azidoacetic acid NHS ester
  • CAS No.:824426-32-6

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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Azidoacetic acid NHS ester Basic information
Product Name:Azidoacetic acid NHS ester
Synonyms:Azidoacetic acid NHS ester;(2,5-dioxopyrrolidin-1-yl) 2-azidoacetate;2-Azidoacetic acid 2,5-dioxo-1-pyrrolidinyl ester;NHS-Azide;NHS-Ac-N3;Aeide-C1-NHS ester;Azidoacetic acid NHS ester,2-Azidoacetic acid 2,5-dioxo-1-pyrrolidinyl ester;2,5-Pyrrolidinedione, 1-[(azidoacetyl)oxy]-
CAS:824426-32-6
MF:C6H6N4O4
MW:198.14
EINECS:
Product Categories:
Mol File:824426-32-6.mol
Azidoacetic acid NHS ester Chemical Properties
Melting point 132-133o C
storage temp. -20°C
solubility Chloroform (Slightly)
form powder or crystals
color White to Off-White
Safety Information
MSDS Information
Azidoacetic acid NHS ester Usage And Synthesis
DescriptionAzidoacetic acid NHS ester is a compound containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
UsesAzidoacetic acid NHS ester is a simple azido-containing reagent with an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines at pH 7-9 forming a stable amide bond. The azide allows for chemoselective ligation with an alkyne or cyclooctyne. It is generally used to functionalize amines and amino acids with azidoacetyl groups. It is generally used in click chemistry applications.
Azidoacetic acid NHS ester Preparation Products And Raw materials

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