(S)-AMPA

(S)-AMPA
  • CAS No.:83643-88-3
Other grades of this product :
(S)-AMPA Basic information
Product Name:(S)-AMPA
Synonyms:(S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(S)-ALPHA-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID;(S)-AMPA;(S)-amino-3-hydroxy-5-methylisoxazolepropionic acid;(S)-A-amino-3-hydroxy-5-methylisoxazole -4-propio;(S)-A-AMINO-3-HYDROXY-5-METHYLISOXAZOLE -4-PROPIONI;(s)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid
CAS:83643-88-3
MF:C7H10N2O4
MW:186.17
EINECS:
Product Categories:Glutamate receptor;Apoptosis Inducers;Glutamate
Mol File:83643-88-3.mol
(S)-AMPA Chemical Properties
alpha D28 -21 ±2° (c = 0.19 in water)
density 1.386±0.06 g/cm3(Predicted)
storage temp. Store at RT
form White to off-white powder.
pka2.15±0.10(Predicted)
CAS DataBase Reference83643-88-3(CAS DataBase Reference)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36/37/39
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
(S)-AMPA Usage And Synthesis
Uses(S)-AMPA is an analogue for AMPA (A611500) a specific agonist for the AMPA receptor which mimics the glutamate receptor.
UsesActive enantiomer of AMPA that induces apoptosis in cortical neurons
Uses(S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice.
General DescriptionAMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC).
Biological ActivityActive enantiomer of AMPA (EC 50 = 3.5 μ M). Also available as part of the AMPA Receptor Tocriset™ .
Biochem/physiol ActionsActive enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors.
(S)-AMPA Preparation Products And Raw materials

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