c-GpAp

c-GpAp
  • CAS No.:849214-04-6
Other grades of this product :
c-GpAp Basic information
Product Name:c-GpAp
Synonyms:c-GpAp;di-GAMP;di-cGAMP;cGAMP (Cyclic GMP-AMP;3''-Guanylic acid, adenylyl-(3''?5'')-, cyclic nucleotide;3',3'-Cyclic guanosine monophosphate-adenosine monophosphate;cGAMP;3'3'-cGAMP
CAS:849214-04-6
MF:C20H24N10O13P2
MW:674.41
EINECS:
Product Categories:Nucleotides, Bases & Related Reagents, Derivatives
Mol File:849214-04-6.mol
c-GpAp Chemical Properties
Boiling point 1159.9±75.0 °C(Predicted)
density 2.61±0.1 g/cm3(Predicted)
storage temp. -20°C
form powder
pka0.96±0.70(Predicted)
color white to beige
Safety Information
MSDS Information
c-GpAp Usage And Synthesis
Usesc-GpAp induces the production of interferons, a usual response to triggers in the cytoplasm of mammalian cells by the presence of DNA.
UsescGAMP sodium salt has been used in cGAS-cGAMP Activity Assay.
Biochem/physiol ActionscGAMP induces the formation of cytokines (interferon-β, interferon-γ), activation of dendritic cells and CD8+ T cell cross priming. Through this action, it promotes innate immune response. cGAMP possesses antitumor activity and is prefered for immunotherapy in cancer treatment.
c-GpAp Preparation Products And Raw materials

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