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| Dimethylenastron Basic information |
| Product Name: | Dimethylenastron | | Synonyms: | Dimethylenastron;2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone;Eg5 Inhibitor III(Dimethylenastron);Eg5 Inhibitor III, Dimethylenastron - CAS 863774-58-7 - Calbiochem;Dimethylenastron - Eg5 inhibitor III;Eg5 Inhibitor III;enastron;5(1H)-Quinazolinone, 2,3,4,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo- | | CAS: | 863774-58-7 | | MF: | C16H18N2O2S | | MW: | 302.39 | | EINECS: | | Product Categories: | | Mol File: | 863774-58-7.mol |
| Dimethylenastron Chemical Properties |
| Boiling point | 475.6±55.0 °C(Predicted) | | density | 1.34±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble15mg/mL, clear | | pka | 9.59±0.10(Predicted) | | form | powder | | color | white to beige |
| Dimethylenastron Usage And Synthesis |
| Uses | Dimethylnasetron is an inhibitor of mitotic motor kinesin Eg5, triggering apoptosis and upregulates Hsp-70 in human myeloma cells. | | Biochem/physiol Actions | Dimethylenastron is specific, reversible inhibitor of the mitotic motor kinesin Eg5. Dimethylenastron inhibits bipolar spindle formation, and inhibits proliferation, migration and invasion of several pancreatic cancer cell lines in cell based assays. |
| Dimethylenastron Preparation Products And Raw materials |
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