ANTI-AMYLOID, BETA

ANTI-AMYLOID, BETA
  • CAS No.:879564-86-0
Other grades of this product :
ANTI-AMYLOID, BETA Basic information
Product Name:ANTI-AMYLOID, BETA
Synonyms:Anti-amyloid beta A4 protein precursor, AAA;Anti-APPI;Anti-CTFgamma;Anti-CVAP;Anti-PN2;Anti-APP (N-terminal region) antibody produced in rabbit;PAN BETA-AMYLOID (AB-1) POLYCLONAL ANTIBODY;MONOCLONAL ANTI-BETA-AMYLOID
CAS:879564-86-0
MF:C11H10ClNO2
MW:223.66
EINECS:
Product Categories:
Mol File:879564-86-0.mol
ANTI-AMYLOID, BETA Chemical Properties
storage temp. −20°C
solubility DMSO: ≥50mg/mL
form buffered aqueous solution
color white to off-white
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
ANTI-AMYLOID, BETA Usage And Synthesis
UsesThe antibody is useful in immunohistochemistry, immunoblotting, ELISA, and competitive ELISA. Also, this antibody has been used to neutralize Aβ assemblies in brains of transgenic mice expressing a mutant form of amyloid precursor protein, and for in vivo deep tissue imaging using near-IR optical spectrum.
General DescriptionThe antibody reacts specifically with β-amyloid protein. The epitope recognized by the antibody resides within amino acids 1-12 of the β-amyloid protein. It specifically stains amyloid plaques within the cortex and amyloid deposits in blood vessels using formic acid-treated, formalin-fixed, paraffin-embedded, and Methacarn-fixed sections of human Alzheimer′s disease (AD) brain tissue.
Biochem/physiol Actionsβ-amyloid gene acts as the substrate of insulin-degrading enzyme (IDE). It plays a major role in the pathogenesis of Alzheimer′s disease (AD) and type 2 diabetes mellitus (DM2).
ANTI-AMYLOID, BETA Preparation Products And Raw materials

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