Other grades of this product :
| CGP 52608 Basic information |
| Product Name: | CGP 52608 | | Synonyms: | CGP 52608;1-[3-Allyl-4-oxo-thiazolidine-2-ylidene]-4-methyl-thiosemicarbazone;N-Methyl-2-[4-oxo-3-(2-propen-1-yl)-2-thiazolidinylidene]-hydrazinecarbothioamide;Hydrazinecarbothioamide, N-methyl-2-[4-oxo-3-(2-propen-1-yl)-2-thiazolidinylidene]-;CGP 52608 >=98%, solid | | CAS: | 87958-67-6 | | MF: | C8H12N4OS2 | | MW: | 244.34 | | EINECS: | | Product Categories: | | Mol File: | 87958-67-6.mol |
| CGP 52608 Chemical Properties |
| storage temp. | -20°C | | solubility | DMSO: >30mg/mL | | form | solid |
| CGP 52608 Usage And Synthesis |
| Uses | CGP 52608 has been used as a RAR related orphan receptor α (RORα) synthetic agonist in THP-1 macrophages, in human monocyte cells THP1 and somatic testicular cells. | | Biochem/physiol Actions | CGP 52608 is a thiazolidine derivative and an antiarthritic compound. It possesses immunostimulatory functionality and elicits antiproliferative effect in colon tumors. It is cytotoxic towards neural cell lines. CGP 52608 induces apoptosis in tumor and also favors G0-G1 cell cycle phase accumulation in neural cell lines. |
| CGP 52608 Preparation Products And Raw materials |
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