2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
  • CAS No.:890842-28-1
Other grades of this product :
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Basic information
Product Name:2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
Synonyms:GSK650394 (Free base);2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid;GSK 650394;SGK inhibitor GS650394;CS-1142;Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-;6-O-α-D-Glucopyranosyl-D-glucose
CAS:890842-28-1
MF:C25H22N2O2
MW:382.45
EINECS:
Product Categories:Inhibitors
Mol File:890842-28-1.mol
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Chemical Properties
storage temp. room temp
solubility DMSO: soluble20mg/mL, clear
form powder
color white to beige
Safety Information
WGK Germany 3
MSDS Information
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Usage And Synthesis
UsesGSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor.
Biochem/physiol ActionsGSK-650394 has an IC50 value of 62?nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103?nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells.
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Preparation Products And Raw materials

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