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| 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE Basic information |
| Product Name: | 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE | | Synonyms: | 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE;A 438079 HYDROCHLORIDE;A 438079;3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine;3-{[5-(2,3-DICHLOROPHENYL)-1H-1,2,3,4-TETRAZOL-1-YL]METHYL}PYRIDINE;Pyridine, 3-[[5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl]methyl]-;A 438079 HCI;A 438079 hydrochlori | | CAS: | 899507-36-9 | | MF: | C13H9Cl2N5 | | MW: | 306.15 | | EINECS: | | Product Categories: | | Mol File: | 899507-36-9.mol |
| 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE Chemical Properties |
| storage temp. | Desiccate at RT | | solubility | Soluble in DMSO |
| 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE Usage And Synthesis |
| Uses | 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine is a 1-Benzyl-5-aryltetrazole derivative and potential antagonists for the P2X7 receptor. | | Biological Activity | Competitive P2X 7 receptor antagonist (pIC 50 = 6.9 for the inhibition of Ca 2+ influx in the human recombinant P2X 7 cell line). Devoid of activity at other P2 receptors (IC 50 >> 10 μ M). Possesses antinociceptive activity in models of neuropathic pain in vivo . |
| 3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE Preparation Products And Raw materials |
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![3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE](/img/899507-36-9.jpg "3-[[5-(2,3-DICHLOROPHENYL)-1H-TETRAZOL-1-YL]METHYL]PYRIDINE HYDROCHLORIDE")
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