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| URICASE Basic information |
| URICASE Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder | | Water Solubility | Hardly soluble in water, slightly soluble in buffer alkaline solution. | | Merck | 13,9944 | | EPA Substance Registry System | Oxidase, urate (9002-12-4) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | YU7100000 | | F | 10-21 | | TSCA | Yes | | HS Code | 35079090 |
| URICASE Usage And Synthesis |
| Chemical Properties | White powder | | Uses | In the determination of serum and urine uric acid. | | Uses | Uricase is very important for the determination of uric acid in biological fluids. Uricase is an important medical enzyme which can be used to determine urate in clinical analysis. The enzyme Urate oxidase (UO) catalyzes the oxidation of uric acid to 5-hydroxyisourate. | | Uses | Uricase from Arthrobacter globiformis has been used for coating the electrodes in - biosensor fabrication for the detection of uric acid in urine samples. It has also been used for analysing the effect of Zn, Cu, Mg, and Mn ions on uricase. | | General Description | Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment. | | Biochem/physiol Actions | Uricase catalyzes the oxidation of uric acid to 5-hydroxyisourate, which subsequently forms (S)-allantoin. It is involved in purine metabolism, urate degradation and (S)-allantoin formation . |
| URICASE Preparation Products And Raw materials |
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