PROTAMINE SULFATE

PROTAMINE SULFATE
  • CAS No.:9009-65-8
Other grades of this product :
PROTAMINE SULFATE Basic information
Product Name:PROTAMINE SULFATE
Synonyms:Protamin sulfate;ProtamineSulphateExSalmonRoe;PROTAMINE SULFATE SALT;Protamine sulfate, Salmine sulfate from salmon sperm;Protamine sulfate 1g [9009-65-8];Ccris 8521;Protamina solfato;Protamina solfato [dcit]
CAS:9009-65-8
MF:H2O4S
MW:0
EINECS:618-450-7
Product Categories:
Mol File:Mol File
PROTAMINE SULFATE Chemical Properties
storage temp. -20°C
solubility H2O: 10 mg/mL
form amorphous powder
color white
Water Solubility It is sparingly soluble in water.
Sensitive Hygroscopic
EPA Substance Registry SystemProtamines, sulfates (9009-65-8)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
RTECS VO9470000
21-10
TSCA Yes
HS Code 35040090
MSDS Information
ProviderLanguage
SigmaAldrich English
PROTAMINE SULFATE Usage And Synthesis
Chemical PropertiesWhite or almost white, hygroscopic powder.
UsesIt is suitable for personal care, cosmetic and pharmaceutical applications. It is used widely to reverse the anticoagulant effects of heparin. It acts as a heparin antagonist. It is also a weak anticoagulant. It may be used for the removal of DNA from protein samples or the purification of DNA binding proteins. Protamine sulfate may also be used as an alternative to polybrene in retroviral mediated gene transfer. Protamine sulfate has antibacterial properties and inhibits pepsin activity. Protamine sulfate and other polycations have been shown to inhibit the classical pathway of complement. It neutralizes the anticoagulant activity of heparin, and inhibits turnover of lipoproteins by lipoprotein lipase. The aggregation of erythrocytes in the presence of protamine sulfate, for application to the prediction of MN phenotypes, has been investigated.
UsesAntidote (to heparin).
PROTAMINE SULFATE Preparation Products And Raw materials
Raw materialsDiethyl ether-->Talc-->ASPHALTUM-->PROTAMINE SULFATE

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