β-N-AcetylglucosaMinidase

β-N-AcetylglucosaMinidase
  • CAS No.:9012-33-3
Other grades of this product :
β-N-AcetylglucosaMinidase Basic information
Product Name:β-N-AcetylglucosaMinidase
Synonyms:N-ACETYL-BETA-D-GLUCOSAMINIDASE;N-ACETYL-BETA-D-GLYCOSAMINIDE-N-ACETYLGLUCOSAMINOHYDROLASE;NAG;BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE;BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE, STREPTOCOCCUS PNEUMONIAE;BETA-N-ACETYLGLUCOSAMINIDASE;BETA-N-ACETYLGLUCOSAMINIDASE H;BETA-N-ACETYLHEXOSAMINIDASE
CAS:9012-33-3
MF:NULL
MW:0
EINECS:232-730-2
Product Categories:
Mol File:Mol File
β-N-AcetylglucosaMinidase Chemical Properties
density 1.37[at 20℃]
vapor pressure 0.004Pa at 25℃
storage temp. 2-8°C
form lyophilized powder
Water Solubility 125g/L at 25℃
LogP-1.3 at 20℃
Safety Information
Hazard Codes B
Risk Statements 20/22-24-37/38-41-42
Safety Statements 53-26-36/37/39-45
WGK Germany 3
10
MSDS Information
ProviderLanguage
SigmaAldrich English
β-N-AcetylglucosaMinidase Usage And Synthesis
Usesβ -N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer’s Disease 1 . Acetylglucosaminidase from Canavalia ensiformis has been used to study enzymic detachment of biofilms.
UsesBovine kidney β-N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer′s Disease .
Flammability and ExplosibilityNotclassified
Biochem/physiol Actionsβ-N-Acetylglucosaminidase from Streptococcus pneumoniae is an extracellular glycosidase and has broad specificity over the β1-3 and β1-6 linkages present in mucins. It belongs to the glycoside hydrolase family 85 (GH85). Also called endo-β-N-acetylglucosaminidase, it cleaves at the asparagine residue of the di-N-acetylchitobiose structure in oligosaccharides and acts on fucosylated N-glycan core. Its deglycosylation functionality is exploited in studying functions of glycoproteins.
Purification MethodsPurify it by chromatography on DEAD-Biogel, hydroxylapatite chromatography and gel filtration through Sephacryl S200. Two isoforms: a hexosaminidase EI with Km 177WM
β-N-AcetylglucosaMinidase Preparation Products And Raw materials

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