heparinase I

heparinase I
  • CAS No.:9025-39-2
Other grades of this product :
heparinase I Basic information
Product Name:heparinase I
Synonyms:HEPARIN LYASE I;HEPARINASE;HEPARINASE I;EC 4.2.2.7;Neutralase;Lyase, heparin;Heparin lyaseI, Heparinase;HeparinaseI from Flavobacterium heparinum,Heparin lyaseI, Heparinase
CAS:9025-39-2
MF:NULL
MW:0
EINECS:
Product Categories:
Mol File:Mol File
heparinase I Chemical Properties
storage temp. -20°C
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
heparinase I Usage And Synthesis
UsesHeparinase I from Flavobacterium heparinum has been used:
  • in the digestion of plasma samples
  • to study the effect of medium, washing and sonication on the infectivity of Chlamydia pneumonia
  • in enzymatic removal of heparan sulfate from the surface of human rhabdomyosarcoma cells
Biochem/physiol ActionsHeparinase I from Flavobacterium heparinum acts by cleaving the α-glycoside linkage at AT III binding site in heparin. This results in small oligosaccharide fragments and heparinase I neutralizes the protein′s action of anticoagulation. Therefore it might replace the use of protamine in reversing heparin induced anticoagulation after coronary artery bypass surgery. Heparinase I possesses a half-life of 15-18 minutes.
heparinase I Preparation Products And Raw materials

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