Other grades of this product :
| Product Name: | EC 1.1.1.1 | | Synonyms: | ALCOHOL DEHYDROGENASE extrapure for biochemistry;ADH, Alcohol:NAD+ oxidoreductase;Alcohol dehydrogenase-Agarose from baker's yeast (S.cerevisiae);Alcohol Dehydrogenase from Candida parapsilosis;ADH, Alcohol Dehydrogenase from horse liver, Alcohol:NAD+ oxidoreductase, HLADH;Alcohol Dedydrogenase,from Yeast;Alcohol dehydrogenase;ADH, NAD+ oxidoreductase | | CAS: | 9031-72-5 | | MF: | n.a. | | MW: | 0 | | EINECS: | 232-870-4 | | Product Categories: | Oxidoreductases;Specialty Enzymes;Oxido-Reductase;Biochemistry;Enzyme | | Mol File: | Mol File |
| EC 1.1.1.1 Chemical Properties |
| RTECS | SZ5999500 | | storage temp. | -20°C | | solubility | H2O: soluble1.0mg/mL, clear to slightly hazy, colorless to faintly yellow | | form | solution | | color | slightly beige | | Water Solubility | Soluble in water. | | Sensitive | Hygroscopic | | EPA Substance Registry System | Dehydrogenase, alcohol (9031-72-5) |
| WGK Germany | 3 | | F | 3-10-21 | | TSCA | Yes | | HS Code | 35079090 |
| EC 1.1.1.1 Usage And Synthesis |
| Description | Alcohol dehydrogenases (ADH) (EC 1.1.1.1) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+) to NADH. In humans and many other animals, they serve to break down alcohols that otherwise are toxic, and they also participate in generation of useful aldehyde, ketone, or alcohol groups during biosynthesis of various metabolites. In yeast, plants, and many bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation to ensure a constant supply of NAD+. | | Properties | The alcohol dehydrogenases comprise a group of several isozymes that catalyse the oxidation of primary and secondary alcohols to aldehydes and ketones, respectively, and also can catalyse the reverse reaction.In mammals this is a redox (reduction/oxidation) reaction involving the coenzyme nicotinamide adenine dinucleotide (NAD+). | | Applications | In biotransformation, alcohol dehydrogenases are often used for the synthesis of enantiomerically pure stereoisomers of chiral alcohols.Often, high chemo- and enantioselectivity can be achieved. In fuel cells, alcohol dehydrogenases can be used to catalyze the breakdown of fuel for an ethanol fuel cell. | | Uses | Alcohol dehydrogenase catalyzes the reaction: RCH2OH +NAD+ ? RCHO + NADH + H+ It facilitates the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). In biotransformation, alcohol dehydrogenases are often used for the synthesis of enantiomerically pure stereoisomers of chiral alcohols. | | General Description | This product has been enhanced for energy efficiency and waste prevention when used in fuel cell research. | | Biochem/physiol Actions | Alcohol dehydrogenase catalyzes the oxidative conversion of alcohol into aldehyde. It has a homodimeric structure with a co-enzyme binding domain at the C-terminal and an N-terminal catalytic domain. The active site is located at the interdomain cleft. Binding of NAD+ in the active site causes conformational changes which create the binding site for the alcohol substrate. |
| EC 1.1.1.1 Preparation Products And Raw materials |
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