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| EC 4.2.1.2 Basic information |
| Product Name: | EC 4.2.1.2 | | Synonyms: | L-MALATE HYDROLYASE;FUMARASE;FUMARATE HYDRATASE;EC 4.2.1.2;fumarase from porcine heart;fumarase from rabbit liver;Hydratase, fumarate;FUMARASE PRESTAINED FROM PORCINE HEART | | CAS: | 9032-88-6 | | MF: | | MW: | 0 | | EINECS: | 232-887-7 | | Product Categories: | | Mol File: | Mol File |
| EC 4.2.1.2 Chemical Properties |
| EC 4.2.1.2 Usage And Synthesis |
| Uses | Fumarase from porcine heart has been used:- as a positive control in isocitrate dehydrogenase and α-ketoglutarate dehydrogenase assay
- for immobilized enzyme based stability assay
- in fumarate hydratase assays in human lung carcinoma cells (A549)
| | Definition | An enzyme that catalyzes the interconversion of
fumaric acid and malic acid. It is an important reactant in the tricarboxylic acid cycle. | | General Description | Fumarase (FH in human) is a well-known tricarboxylic-acid-cycle enzyme found in both the cytoplasm and mitochondria of all eukaryotes. | | Biochem/physiol Actions | Fumarase catalyzes the reversible hydration of fumarate to malate. In its mitochondrial form, fumarate is involved in the Krebs Cycle, while the cytosolic form is involved in amino acid metabolism. |
| EC 4.2.1.2 Preparation Products And Raw materials |
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