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| EC 1.6.2.4 Basic information |
| Product Name: | EC 1.6.2.4 | | Synonyms: | EC 1.6.2.4;CYTOCHROME P450 REDUCTASE;CYTOCHROME P450 REDUCTASE HUMAN;napdh-cytochromep-450reductase;NADPH: FERRIHEMOPROTEIN OXIDOREDUCTASE;cytochrome P450 reductase from rabbit*liver induc;CYTOCHROME P450 REDUCTASE FROM RABBITLIV ER INDUCED;cytochrome p450 reductase from rabbit liver induced with phenobarbital | | CAS: | 9039-06-9 | | MF: | | MW: | 0 | | EINECS: | | Product Categories: | | Mol File: | Mol File |
| EC 1.6.2.4 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution |
| EC 1.6.2.4 Usage And Synthesis |
| Uses | Human cytochrome P450 reductase has been used in a study to assess the biocatalytic synthesis and structure elucidation of cyclized metabolites of the deacetylase inhibitor panobinostat (LBH589). Human cytochrome P450 reductase has also been used in a study to investigate the effects of coupled motions on electrons along the human microsomal P450 chains. | | General Description | This human, recombinant protein is isolated from insect cells infected with a baculovirus containing the cDNA for human cytochrome P450 reductase. It is purified by affinity chromatography. | | Biochem/physiol Actions | The enzyme catalyses electron transfer to cytochrome P450. This system plays a major role in detoxification of drugs and xenobiotics, activation of carcinogens, and metabolism of endogenous substrates such as steroids. |
| EC 1.6.2.4 Preparation Products And Raw materials |
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