ABD-F

ABD-F
  • CAS No.:91366-65-3
Other grades of this product :
ABD-F Basic information
Product Name:ABD-F
Synonyms:4-Fluoro-7-sulfobenzofurazan;[=4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for DeterMination of Thiols];ABD-F 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol;4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, 98%, derivatization grade;7-Fluorobenzoc1,2,5oxadiazole-4-sulfonamide;4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, derivatization grade;ABD-F
CAS:91366-65-3
MF:C6H4FN3O3S
MW:217.18
EINECS:
Product Categories:Chemical and pharmaceutical intermediates;pharmaceutical intermediates;Analytical Chemistry;Fluorescence Detection (HPLC Labeling Reagents);HPLC Labeling Reagents;Mercapto Group Labeling Reagents for Fluorescence HPLC;Fluorescent Labels and Indicators;Fluorescent Labels & Indicators;MTS & Sulfhydryl Active Reagents
Mol File:91366-65-3.mol
ABD-F Chemical Properties
Melting point 143-145°C
storage temp. -20°C
solubility DMSO: soluble
form White to yellow crystalline powder.
color Off-White to Pale Yellow
BRN 5035147
Stability:Light Sensitive
InChIKeyXROXHZMRDABMHS-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36/37/39-24/25
WGK Germany 3
3-10
Hazard Note Irritant
HS Code 29350090
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
ABD-F Usage And Synthesis
Chemical PropertiesLight Yellow Solid
UsesHighly reactive fluorogenic reagent for the labeling of thiols for HPLC. ABD-F is nonfluorescent until reacted with thiols and therefore can be used to quantitate thiols in solution, as well as thiols separated by HPLC or TLC.
UsesA water soluble pH dependent bifunctional fluorogenic reagent for the sensitive and specific detection of protein thiols. ABD-F is highly reactive and specific for protein thiols, and its selectivity is superior to that of other sulfhydryl-reactive fluorophores such as fluorescein maleimide, 5-iodoacetamidofluorescein, 5-I-AEDANS, dansylaziridine, and bimane. Fluorescence: max Abs. l = 385nm, max Em. l = 520nm; Molar Abs. > 4.5x103 (ca. 315nm)
UsesReagent for fluorimetric assay of thiols.
General Description4-Fluoro-7-sulfamoylbenzofurazan is a fluorescent reagent, which directly links to the sulfur atom of thiols without a flexible alkyl chain. It is used to detect low molecular thiols using high performance liquid chromatography.
ABD-F Preparation Products And Raw materials

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