4-(N-Maleimido)benzophenone

4-(N-Maleimido)benzophenone
  • CAS No.:92944-71-3
Other grades of this product :
4-(N-Maleimido)benzophenone Basic information
Product Name:4-(N-Maleimido)benzophenone
Synonyms:4-(N-MALEIMIDO)BENZOPHENONE;4-(MALEIMIDO)BENZOPHENONE;AKOS MSC-0079;BENZOPHENONE-4-MALEIMIDE;1-(4-benzoylphenyl)pyrrole-2,5-dione;N-(4-benzoylphenyl)maleimide;4-(Maleinimido)benzophenone;1-(4-BENZOYLPHENYL)-1H-PYRROLE-2,5-DIONE
CAS:92944-71-3
MF:C17H11NO3
MW:277.27
EINECS:
Product Categories:Maleimide Derivatives;Cross Linking Reagents;MTS & Sulfhydryl Active Reagents;Linking Reagents;Aromatics;Heterocycles;Heterobifunctional Cross-Linking Reagents;Protein Modification;Protein Structural Analysis;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Crosslinking;Cyclic Imides;Organic Building Blocks;Proteomics
Mol File:92944-71-3.mol
4-(N-Maleimido)benzophenone Chemical Properties
Melting point 155-157°C
Boiling point 472.9±28.0 °C(Predicted)
density 1.330±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility chloroform: 50 mg/mL
form Solid
pka-3.80±0.20(Predicted)
color Light Beige
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29251900
MSDS Information
ProviderLanguage
SigmaAldrich English
4-(N-Maleimido)benzophenone Usage And Synthesis
Chemical PropertiesLight Beige Solid
Uses4-(N-Maleimido)benzophenone can be used as a sulfhydryl reactive heterobifunctional photocrosslinking reagent. It generates photoactivatable conjugates from thiols
UsesMaleimide-containing benzophenone as photoinitiator
UsesA heterobifunctional cross-linking reagent containing a sulfhydryl-specific group and a photo-active group. Typically, coupled initially by thioether to molecule containing free sulfhydryl buffered at pH 6.8 (6.5-7.0). Second bonding occurs during UV irradiation (250 nm) via diradical excited state. Benzophenones demonstrate greater specificity for C-H insertion and are more stable in water than analogous reagents. In general they are more efficient in attachment because they may be repeatedly irradiated; however, a more intense irradiation may be required. The benzophenone is not sensitive to
4-(N-Maleimido)benzophenone Preparation Products And Raw materials

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