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| LY 294002 Basic information |
| Product Name: | LY 294002 | | Synonyms: | LY 294002, Hydrochloride Salt, >99%;LY 294002, HYDROCHLORIDE SALT;LY-294,002 hydrochloride, 98%, selective inhibitor of PI 3-kinase;LY-294,002 hydrochloride, ≥98% (HPLC) | | CAS: | 934389-88-5 | | MF: | C19H18ClNO3 | | MW: | 343.80412 | | EINECS: | | Product Categories: | | Mol File: | 934389-88-5.mol |
| LY 294002 Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: >5mg/mL | | form | solid | | color | white to off-white |
| WGK Germany | 3 | | HS Code | 29349990 |
| LY 294002 Usage And Synthesis |
| Uses | LY 294002 Hydrochloride is a highly selective inhibitor of Phosphatidylinositol 3-kinase (PI3K). It is a salt analogue of LY 294002 (L486590). | | General Description | LY-294,002 hydrochloride is a derivative of the flavonoid, quercetin and elicits higher inhibition on the enzyme phosphoinositide 3-kinase (PI3K). LY-294,002 inhibits nuclear factor kappa B signaling in macrophages. It elevates expression of autophagosomal protein LC3 and promotes apoptosis in gastric and nasopharyngeal cancer cells. LY-294,002 modulates action potential repolarization and improves myocyte contractility. |
| LY 294002 Preparation Products And Raw materials |
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